Looking at isolation and games brings to mind the silent hill 4 game (the room) as the character (Henry) is stuck in this room and he cant get out but this is not just physical it’s a psychological isolation because he’s not sure if he is in a dream or not and he cant get out of the dream. So this is not an isolation of space as he goes many places but more an isolation of the mind dreaming in a room.
The atmosphere is made up with rust and blood to give extra atmosphere to the dark environment, as soon as you play it you get that creepy feeling with the game.